solgar
multiple

solgar
multiple
Why
take solgar multiple vitamins?
Multiple
Vitamin-Mineral Supplements
References
What do they do? Multiple vitamin-mineral (MVM) supplements contain
a variable number of essential and/or non-essential nutrients. Their
primary purpose is to provide a convenient way to take a variety
of supplemental nutrients from a single product, in order to prevent
vitamin or mineral deficiencies, as well as to achieve higher intakes
of nutrients believed to be of benefit above typical dietary levels.
Many
MVMs contain at least 100% of the Daily Value (DV) or the U.S. Recommended
Dietary Allowance (USRDA) of all vitamins that have been assigned
these recommended values. Mineral levels may be lower, or in the
case of high potency MVMs, most or all mineral levels may also be
at 100% of DV or USRDA. Micronutrients that should be included in
a complete MVM are vitamin A, vitamin B-complex (thiamine, riboflavin,
niacin and/or niacinamide, vitamin B6, folate, vitamin B12, pantothenic
acid, and biotin), vitamin C, vitamin D, vitamin E, and vitamin
K, and the minerals calcium, magnesium, zinc, iodine, selenium,
copper, manganese, chromium, molybdenum, and possibly iron. Phosphorus
is another essential dietary mineral, but it is so abundant in the
human diet that deficiencies are virtually unknown, and it does
not need to be included in an MVM formula.
Potassium
is an unusual case, as adequate amounts of potassium cannot, by
law, be sold in nonprescription products. Thus potassium, when included
in an MVM formula, represents only a trivial amount. MVMs may contain
iron, but these should be taken only by people who have been diagnosed
as having, or being at high risk of, iron deficiency, or who have
a history of frequent iron deficiencies.
Some
nutrients may be beneficial at levels above what is possible to
obtain from diet alone, and an MVM formula can provide these levels
as well. Nutrients that may be useful to most people in larger amounts
include vitamin C, folic acid, and calcium. Vitamin E has long been
thought to protect against heart disease beginning at 100 IU per
day, but a recent study has suggested that amounts of vitamin E
available in MVM formulas may not be effective (see Atherosclerosis).
Large amounts of vitamin B1, vitamin B2, vitamin B3, and pantothenic
acid are often included in MVM formulas. Some people claim to experience
improvements in mood, energy, and/or overall well-being when taking
higher-than-RDA amounts of B vitamins. However, there is little
scientific research to support those observations.
The
common inclusion of the non-essential nutrient beta-carotene in
MVMs remains speculative. The synthetic beta-carotene found in most
MVMs clearly does not prevent cancer and may increase the risk of
lung cancer in smokers. Therefore, the inclusion of synthetic beta-carotene
in MVM formulas is of questionable value, and it should be avoided
by smokers. This concern is validated by the results of a large
study which found that male smokers who use multivitamins had a
higher death rate from cancer than male smokers who did not use
a multivitamin, presumably due to the synthetic beta-carotene content.1
On the other hand, because beta-carotene can be converted to vitamin
A without causing vitamin A toxicity, some manufacturers use beta-carotene
as a source of vitamin A. However, natural beta-carotene and several
other carotenoids may be helpful in preventing certain diseases,
including some cancers.2 3 4 Increasingly, natural beta-carotene
and several other carotenoids are found in higher quality MVMs.
Another
class of non-essential nutrients is the flavonoids, which have antioxidant
and other properties and have been reported by some,5 though not
all,6 researchers to be linked with a reduced risk of heart disease.
MVM supplements also frequently include other nutrients of uncertain
benefit in the small amounts supplied, such as choline, inositol,
and various amino acids.
Preliminary7
and double-blind8 trials have shown that women who use an MVM containing
folic acid beginning three months before becoming pregnant and continuing
through the first three months of pregnancy, have a significantly
lower risk of having babies with neural tube defects (e.g., spina
bifida) and other congenital defects.
In
one double-blind trial, schoolchildren received, for three months,
a daily low-dose vitamin-mineral tablet containing 50% of the USRDA
for most essential vitamins and the minerals, iron, zinc, chromium,
manganese, molybdenum, selenium, and copper.9 The subjects were
“working class,” primarily Hispanic, children, aged 6 to 12 years.
Dramatic gains in certain measures of IQ were observed in about
20% of the supplemented children. These gains may have been due
to the correction of specific nutrient deficiencies (for example,
iron) found in these children. However, it was not possible in this
study to identify which nutrients caused the increases in IQ.
Use
of a multivitamin has been associated with reduced death rates from
cardiovascular disease.10
What
about “one-per-day” multiples? One-per-day multiples are primarily
B-complex vitamins, with both vitamin A and vitamin D included either
at high or low potency, depending on the supplement. The rest of
the formula tends to be low potency. It does not take much of some
of the minerals—for example, copper, zinc, and iron—to offer 100%
or more of what people normally require, so these minerals may appear
at reasonable levels in a one-per-day MVM.
One-per-day
MVMs do not provide sufficient amounts of many nutrient supplements
shown to benefit people eating a Western diet, such as vitamin E,
calcium, magnesium, and vitamin C. One-per-day MVMs should therefore
not be viewed as a way to “cover all bases” in the way that high-potency
MVMs, requiring three or more pills per day, are viewed.
How
much is usually taken? The following table shows the USRDA for nutrients
as well as suggested optimum amounts of each vitamin and mineral
that should be present in a daily MVM supplement for healthy people.
Some people may want to take larger amounts because of specific
health concerns. They should read the individual nutrient sections
to learn about safe upper ranges of supplementation.
Nutrient
Daily Value (includes diet)
Suggested Daily Optimum in an MVM Supplement
Biotin 300 mcg 300 mcg
Calcium 1,000 mg 800–1,000 mg
Chromium 120 mg 120–200 mcg
Copper 2 mg 1–3 mg
Folate 400 mcg 400 mcg
Iodine 150 mcg 150 mcg
Iron 18 mg People should avoid iron supplements unless they have
been diagnosed with having, or being at high risk of, iron deficiency.
Magnesium 400 mg 250–400 mg
Manganese 2 mg 2–5 mg
Molybdenum 75 mcg 75 mcg
Niacin 20 mg 20 mg
Pantothenic acid 10 mg 10 mg
Riboflavin 1.7 mg 1.7 mg
Selenium 70 mcg 100–200 mcg
Thiamine 1.5 mg 1.5 mg
Vitamin A 5,000 IU 5,000 IU (as natural beta-carotene)
Vitamin B6 2 mg 10 mg
Vitamin B12 6 mcg 50 mcg
Vitamin C 60 mg 100–200 mg
Vitamin D 400 IU 400 IU
Vitamin E 30 IU 100–400 IU
Vitamin K 80 mcg 80 mcg
Zinc 15 mg 15–25 mg
Because
one-per-day formulas typically do not contain even the minimum recommended
amounts of some of the nutrients above, multiples requiring several
capsules or tablets per day are preferable. With two- to six-per-day
multiples, intake of pills should be spread out over the day, instead
of taking them all at one sitting. The amount of vitamins and minerals
can be easily increased or decreased by taking more or fewer of
the multiple.
Which
is better—capsule or tablet? Multiples are available as a powder
inside a hard-shell pull-apart capsule, as a liquid inside a soft-gelatine
capsule, or as a tablet.
Most
multiples have all the ingredients mixed together. Occasionally
the B vitamins react with the rest of the ingredients in the capsule
or tablet. This reaction, which is sped up in the presence of moisture
or heat, can cause the B vitamins to “bleed” through the tablet
or capsule, discoloring it and also making the multiple smell. While
the multiple is still safe and effective, the smell is off-putting
and usually not very well tolerated. Liquid multiples in a soft-gel
capsule—or tablets or capsules that are kept dry and cool—do not
have this problem.
Capsules
are usually not as large as tablets, and thus some people find capsules
easier to swallow.
Some
people prefer vegetarian multiples. While some capsules are made
from vegetarian sources, most come from animal gelatine. Vegetarians
need to carefully read the label to ensure they are getting a vegetarian
product.
One
concern people have with tablets is whether they will break down.
Properly made tablets and capsules will both dissolve readily in
the stomach.
What
about timed-release? Some multiples are in timed-release form. The
theory is that releasing vitamins and minerals slowly into the body
over a period of time is better than releasing all of the nutrients
at once. Except for work done on vitamin C—some of which showed
timed-release C was better absorbed than non-timed-release—research
on this question has been lacking. It is possible that some nutrients,
especially minerals, will be poorly absorbed from timed-release
multiples. Also, some doctors have concerns about the safety of
ingesting the chemicals that are used in tablets or capsules to
make them timed-release.
What
about nutrient interactions? Another area of controversy is whether
all of the nutrients in a multiple would be better utilised if they
were taken separately. While certain nutrients compete with each
other for absorption, this is also the case when the nutrients are
supplied in food. For example, magnesium, zinc, and calcium compete;
copper and zinc also compete. However, the body is designed to cope
with this competition, which should not be a problem if multiples
are spread out over the day.
What
about chewables? Unfortunately, multiples do not taste very good.
In order to make chewable multiples palatable, whether for children
or adults, some compromises must be made. First, bad-tasting ingredients
must be reduced or eliminated. Second, the rest of the ingredients
must be masked with a sweetener.
Unless
an artificial sweetener like aspartame (NutraSweet®) or saccharin
is used, the only sweeteners available are sugars. Generally, consuming
sugar is undesirable, and not having it in a chewable dietary supplement
would be preferable. Xylitol, a natural sugar rarely used in chewables
because it is relatively expensive, would be an ideal choice since
it does not cause tooth decay or other known problems.
Some
chewables, such as vitamin C, contain more sugar than any other
ingredient. In such products, the sweetener should be listed as
the first ingredient, but often is not. Care needs to be exercised
when reading labels about chewable vitamins. If it tastes sweet,
it contains sugar or a synthetic sweetener.
When
is the best time to take a multiple? The best time to take vitamins
or minerals is with meals. Multiples taken between meals sometimes
cause stomach upset and are likely not to be as well absorbed.
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