solgar
multiple

solgar
multiple
Why
take solgar multiple vitamins?
Multiple Vitamin-Mineral Supplements
References
What do they do? Multiple vitamin-mineral (MVM) supplements contain
a variable number of essential and/or non-essential nutrients. Their
primary purpose is to provide a convenient way to take a variety
of supplemental nutrients from a single product, in order to prevent
vitamin or mineral deficiencies, as well as to achieve higher intakes
of nutrients believed to be of benefit above typical dietary levels.
Many MVMs contain at least 100% of the Daily Value (DV) or the
U.S. Recommended Dietary Allowance (USRDA) of all vitamins that
have been assigned these recommended values. Mineral levels may
be lower, or in the case of high potency MVMs, most or all mineral
levels may also be at 100% of DV or USRDA. Micronutrients that should
be included in a complete MVM are vitamin A, vitamin B-complex (thiamine,
riboflavin, niacin and/or niacinamide, vitamin B6, folate, vitamin
B12, pantothenic acid, and biotin), vitamin C, vitamin D, vitamin
E, and vitamin K, and the minerals calcium, magnesium, zinc, iodine,
selenium, copper, manganese, chromium, molybdenum, and possibly
iron. Phosphorus is another essential dietary mineral, but it is
so abundant in the human diet that deficiencies are virtually unknown,
and it does not need to be included in an MVM formula.
Potassium is an unusual case, as adequate amounts of potassium
cannot, by law, be sold in nonprescription products. Thus potassium,
when included in an MVM formula, represents only a trivial amount.
MVMs may contain iron, but these should be taken only by people
who have been diagnosed as having, or being at high risk of, iron
deficiency, or who have a history of frequent iron deficiencies.
Some nutrients may be beneficial at levels above what is possible
to obtain from diet alone, and an MVM formula can provide these
levels as well. Nutrients that may be useful to most people in larger
amounts include vitamin C, folic acid, and calcium. Vitamin E has
long been thought to protect against heart disease beginning at
100 IU per day, but a recent study has suggested that amounts of
vitamin E available in MVM formulas may not be effective (see Atherosclerosis).
Large amounts of vitamin B1, vitamin B2, vitamin B3, and pantothenic
acid are often included in MVM formulas. Some people claim to experience
improvements in mood, energy, and/or overall well-being when taking
higher-than-RDA amounts of B vitamins. However, there is little
scientific research to support those observations.
The common inclusion of the non-essential nutrient beta-carotene
in MVMs remains speculative. The synthetic beta-carotene found in
most MVMs clearly does not prevent cancer and may increase the risk
of lung cancer in smokers. Therefore, the inclusion of synthetic
beta-carotene in MVM formulas is of questionable value, and it should
be avoided by smokers. This concern is validated by the results
of a large study which found that male smokers who use multivitamins
had a higher death rate from cancer than male smokers who did not
use a multivitamin, presumably due to the synthetic beta-carotene
content.1 On the other hand, because beta-carotene can be converted
to vitamin A without causing vitamin A toxicity, some manufacturers
use beta-carotene as a source of vitamin A. However, natural beta-carotene
and several other carotenoids may be helpful in preventing certain
diseases, including some cancers.2 3 4 Increasingly, natural beta-carotene
and several other carotenoids are found in higher quality MVMs.
Another class of non-essential nutrients is the flavonoids, which
have antioxidant and other properties and have been reported by
some,5 though not all,6 researchers to be linked with a reduced
risk of heart disease. MVM supplements also frequently include other
nutrients of uncertain benefit in the small amounts supplied, such
as choline, inositol, and various amino acids.
Preliminary7 and double-blind8 trials have shown that women who
use an MVM containing folic acid beginning three months before becoming
pregnant and continuing through the first three months of pregnancy,
have a significantly lower risk of having babies with neural tube
defects (e.g., spina bifida) and other congenital defects.
In one double-blind trial, schoolchildren received, for three months,
a daily low-dose vitamin-mineral tablet containing 50% of the USRDA
for most essential vitamins and the minerals, iron, zinc, chromium,
manganese, molybdenum, selenium, and copper.9 The subjects were
“working class,” primarily Hispanic, children, aged 6 to 12 years.
Dramatic gains in certain measures of IQ were observed in about
20% of the supplemented children. These gains may have been due
to the correction of specific nutrient deficiencies (for example,
iron) found in these children. However, it was not possible in this
study to identify which nutrients caused the increases in IQ.
Use of a multivitamin has been associated with reduced death rates
from cardiovascular disease.10
What about “one-per-day” multiples? One-per-day multiples are primarily
B-complex vitamins, with both vitamin A and vitamin D included either
at high or low potency, depending on the supplement. The rest of
the formula tends to be low potency. It does not take much of some
of the minerals—for example, copper, zinc, and iron—to offer 100%
or more of what people normally require, so these minerals may appear
at reasonable levels in a one-per-day MVM.
One-per-day MVMs do not provide sufficient amounts of many nutrient
supplements shown to benefit people eating a Western diet, such
as vitamin E, calcium, magnesium, and vitamin C. One-per-day MVMs
should therefore not be viewed as a way to “cover all bases” in
the way that high-potency MVMs, requiring three or more pills per
day, are viewed.
How much is usually taken? The following table shows the USRDA
for nutrients as well as suggested optimum amounts of each vitamin
and mineral that should be present in a daily MVM supplement for
healthy people. Some people may want to take larger amounts because
of specific health concerns. They should read the individual nutrient
sections to learn about safe upper ranges of supplementation.
Nutrient
Daily Value (includes diet)
Suggested Daily Optimum in an MVM Supplement
Biotin 300 mcg 300 mcg
Calcium 1,000 mg 800–1,000 mg
Chromium 120 mg 120–200 mcg
Copper 2 mg 1–3 mg
Folate 400 mcg 400 mcg
Iodine 150 mcg 150 mcg
Iron 18 mg People should avoid iron supplements unless they have
been diagnosed with having, or being at high risk of, iron deficiency.
Magnesium 400 mg 250–400 mg
Manganese 2 mg 2–5 mg
Molybdenum 75 mcg 75 mcg
Niacin 20 mg 20 mg
Pantothenic acid 10 mg 10 mg
Riboflavin 1.7 mg 1.7 mg
Selenium 70 mcg 100–200 mcg
Thiamine 1.5 mg 1.5 mg
Vitamin A 5,000 IU 5,000 IU (as natural beta-carotene)
Vitamin B6 2 mg 10 mg
Vitamin B12 6 mcg 50 mcg
Vitamin C 60 mg 100–200 mg
Vitamin D 400 IU 400 IU
Vitamin E 30 IU 100–400 IU
Vitamin K 80 mcg 80 mcg
Zinc 15 mg 15–25 mg
Because one-per-day formulas typically do not contain even the
minimum recommended amounts of some of the nutrients above, multiples
requiring several capsules or tablets per day are preferable. With
two- to six-per-day multiples, intake of pills should be spread
out over the day, instead of taking them all at one sitting. The
amount of vitamins and minerals can be easily increased or decreased
by taking more or fewer of the multiple.
Which is better—capsule or tablet? Multiples are available as a
powder inside a hard-shell pull-apart capsule, as a liquid inside
a soft-gelatine capsule, or as a tablet.
Most multiples have all the ingredients mixed together. Occasionally
the B vitamins react with the rest of the ingredients in the capsule
or tablet. This reaction, which is sped up in the presence of moisture
or heat, can cause the B vitamins to “bleed” through the tablet
or capsule, discoloring it and also making the multiple smell. While
the multiple is still safe and effective, the smell is off-putting
and usually not very well tolerated. Liquid multiples in a soft-gel
capsule—or tablets or capsules that are kept dry and cool—do not
have this problem.
Capsules are usually not as large as tablets, and thus some people
find capsules easier to swallow.
Some people prefer vegetarian multiples. While some capsules are
made from vegetarian sources, most come from animal gelatine. Vegetarians
need to carefully read the label to ensure they are getting a vegetarian
product.
One concern people have with tablets is whether they will break
down. Properly made tablets and capsules will both dissolve readily
in the stomach.
What about timed-release? Some multiples are in timed-release form.
The theory is that releasing vitamins and minerals slowly into the
body over a period of time is better than releasing all of the nutrients
at once. Except for work done on vitamin C—some of which showed
timed-release C was better absorbed than non-timed-release—research
on this question has been lacking. It is possible that some nutrients,
especially minerals, will be poorly absorbed from timed-release
multiples. Also, some doctors have concerns about the safety of
ingesting the chemicals that are used in tablets or capsules to
make them timed-release.
What about nutrient interactions? Another area of controversy is
whether all of the nutrients in a multiple would be better utilised
if they were taken separately. While certain nutrients compete with
each other for absorption, this is also the case when the nutrients
are supplied in food. For example, magnesium, zinc, and calcium
compete; copper and zinc also compete. However, the body is designed
to cope with this competition, which should not be a problem if
multiples are spread out over the day.
What about chewables? Unfortunately, multiples do not taste very
good. In order to make chewable multiples palatable, whether for
children or adults, some compromises must be made. First, bad-tasting
ingredients must be reduced or eliminated. Second, the rest of the
ingredients must be masked with a sweetener.
Unless an artificial sweetener like aspartame (NutraSweet®)
or saccharin is used, the only sweeteners available are sugars.
Generally, consuming sugar is undesirable, and not having it in
a chewable dietary supplement would be preferable. Xylitol, a natural
sugar rarely used in chewables because it is relatively expensive,
would be an ideal choice since it does not cause tooth decay or
other known problems.
Some chewables, such as vitamin C, contain more sugar than any
other ingredient. In such products, the sweetener should be listed
as the first ingredient, but often is not. Care needs to be exercised
when reading labels about chewable vitamins. If it tastes sweet,
it contains sugar or a synthetic sweetener.
When is the best time to take a multiple? The best time to take
vitamins or minerals is with meals. Multiples taken between meals
sometimes cause stomach upset and are likely not to be as well absorbed.
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